Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTDN3LF)

• DTT Name: Nerve growth factor (NGF) DTT Info
• Gene Name: NGF

Molecule-Related Drug & Molecule List

8 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fasinumab	DM5PRLA	Chronic low back pain	MG30.02	Phase 3	[1]
Tanezumab	DMJKWMA	Cancer related pain	MG30	Phase 3	[1]
SAR164877	DMOJLCV	Pain	MG30-MG3Z	Phase 2/3	[2]
CERE-110	DMNW5I9	Alzheimer disease	8A20	Phase 2	[3]
CXB-909	DMUGMFN	Neurodegenerative disorder	8A20-8A23	Phase 1/2	[4]
ABT-110	DM1F50I	Chronic pain	MG30	Phase 1	[2]
MEDI-578	DMPW21Z	Pain	MG30-MG3Z	Phase 1	[2]
NsG-0202	DM1ITDN	Alzheimer disease	8A20	Phase 1	[4]

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nerve growth factor	DMHYQ8K	Alzheimer disease	8A20	Terminated	[5]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] Fate of novel painkiller mAbs hangs in balance.Nat Biotechnol.2011 Mar;29(3):173-4.
• [3] CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease. Curr Opin Mol Ther. 2010 Apr;12(2):240-7.
• [4] Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
• [5] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.