Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTE3RAC)

DTT Name	Dickkopf-related protein 1 (DKK1) DTT Info
Gene Name	DKK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BHQ880	DMSROM4	Multiple myeloma	2A83	Phase 2	[1]
DKN-01	DMOHT5V	Biliary tract cancer	2C17	Phase 2	[2]
PF-04840082	DMDSCQG	Osteoporosis	FB83.0	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood. 2009 Jul 9;114(2):371-9.
2	The anti-DKK1 antibody DKN-01 as an immunomodulatory combination partner for the treatment of cancer. Expert Opin Investig Drugs. 2020 Jul;29(7):639-644.
3	The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis. J Pharmacol Exp Ther. 2010 Apr;333(1):2-13.