General Information of DTT (ID: TTE6YDG)

DTT Name CDC-like kinase 1 (CLK1) DTT Info
Gene Name CLK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Patented Agent(s)
Investigative Drug(s)
1 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
TG003 DMP4HR2 Discovery agent N.A. Patented [1]
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4 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
KH-CB19 DMSOB3U Discovery agent N.A. Investigative [2]
leucettine L41 DMBYND6 Discovery agent N.A. Investigative [3]
ML315 DMNOREK Discovery agent N.A. Investigative [4]
PMID23642479C17 DM4JWMA Discovery agent N.A. Investigative [4]
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Molecule Interaction Atlas

References

1 A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8.
2 Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. Chem Biol. 2011 Jan 28;18(1):67-76.
3 Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. J Med Chem. 2011 Jun 23;54(12):4172-86.
4 Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun15;23(12):3654-61.