Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTEVCT0)

DTT Name Caspase-8 (CASP8) DTT Info
Gene Name CASP8

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
3 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetyl-Ile-Glu-Thr-Asp-aldehyde DM1VE6S Discovery agent N.A. Investigative [1]
Amooranin DMC15DM Autoimmune diabetes 5A10 Investigative [2]
Glionitrin A DM98CSW Solid tumour/cancer 2A00-2F9Z Investigative [2]
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Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 The atomic-resolution structure of human caspase-8, a key activator of apoptosis. Structure. 1999 Sep 15;7(9):1135-43.
2 Glionitrin A, a new diketopiperazine disulfide, activates ATM-ATR-Chk1/2 via 53BP1 phosphorylation in DU145 cells and shows antitumor effect in xenograft model. Biol Pharm Bull. 2014;37(3):378-86.