General Information of DTT (ID: TTEX3SI)

DTT Name MHC class I NK cell receptor 2DL3 (CD158b2) DTT Info
Gene Name KIR2DL3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
3 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
IPH-2101 DMDUVCZ Multiple myeloma 2A83 Phase 2 [1]
IPH-2102 DMPBR0D Acute myeloid leukaemia 2A60 Phase 2 [1]
mab 1-7F9 DMQOBH4 Multiple myeloma 2A83 Phase 2 [2]
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Molecule Interaction Atlas

References

1 Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide. Haematologica. 2015 Feb;100(2):263-8.
2 Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12879-84.