Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTFN95D)

DTT Name	PAK-1 protein kinase (PAK1) DTT Info
UniProt ID	PAK1_HUMAN
Gene Name	PAK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Il-94	DMPNQ27	Discovery agent	N.A.	Investigative	[1]
PMID20005102C1	DMMESBW	Discovery agent	N.A.	Investigative	[2]
RKI-1447	DMGTAWC	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	PAK1: A Therapeutic Target for Cancer Treatment. ACS Med Chem Lett. 2013 Mar 19;4(5):431-2.
2	2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles. Bioorg Med Chem Lett. 2010 Jan 15;20(2):679-83.
3	Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709.