General Information of DTT (ID: TTFPQV7)

DTT Name Galectin-3 (LGALS3) DTT Info
Gene Name LGALS3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
GB0139 DMA8KQR Idiopathic pulmonary fibrosis CB03.4 Phase 2 [1]
GR-MD-02 DM9QF65 Hypertension BA00-BA04 Phase 2 [2]
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2 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide DM592YS Discovery agent N.A. Investigative [3]
PFFFFF DM9AZKE Discovery agent N.A. Investigative [4]
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Molecule Interaction Atlas

References

1 An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE). Am J Respir Crit Care Med. 2023 Jan 15;207(2):138-149.
2 Therapy of experimental NASH and fibrosis with galectin inhibitors. PLoS One. 2013 Dec 18;8(12):e83481.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries. Bioorg Med Chem Lett. 2007 Feb 1;17(3):793-8.