Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTFPVZO)

DTT Name	Long transient receptor potential channel 7 (TRPM7) DTT Info
UniProt ID	TRPM7_HUMAN
Gene Name	TRPM7

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-APB	DM9AKVR	Discovery agent	N.A.	Investigative	[1]
carvacrol	DMINM2D	Discovery agent	N.A.	Investigative	[2]
PIP2	DMOZV7N	Discovery agent	N.A.	Investigative	[3]
waixenicin A	DMB6H35	Discovery agent	N.A.	Investigative	[4]
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Molecule Interaction Atlas

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References

1	LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature. 2001 May 31;411(6837):590-5.
2	Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. Cell Calcium. 2009 Mar;45(3):300-9.
3	The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol. 2002 May;4(5):329-36.
4	Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. J Biol Chem. 2011 Nov 11;286(45):39328-35.