Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTG3K2U)

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TZI-41078	DMKJIDU	Arthritis	FA20	Phase 2	[1]
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2 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CPA-926	DMH5LKS	Arthritis	FA20	Discontinued in Phase 2	[2]
FLM-5011	DMKWTPX	Inflammation	1A00-CA43.1	Discontinued in Phase 1	[3]
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Molecule Interaction Atlas

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References

1	Hydroxylamine analogs of 2,6-di-t-butylphenols: dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors. Bioorg Med Chem. 1995 Apr;3(4):403-10.
2	Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis. J Rheumatol. 1999 Mar;26(3):654-62.
3	Lipoxygenase inhibitor FLM 5011, an effective protectant of myocardial microvessels against ischemia-reperfusion injury. Exp Toxicol Pathol. 2000 Mar;52(1):27-36.