General Information of DTT (ID: TTG84D3)

DTT Name Ephrin type-A receptor 4 (EPHA4) DTT Info
Gene Name EPHA4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
1 Discontinued Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
MEDI-542 DM4G0D5 Solid tumour/cancer 2A00-2F9Z Terminated [1]
------------------------------------------------------------------------------------
2 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID19788238C66 DMCVJK9 Discovery agent N.A. Investigative [2]
PMID23489211C20 DMDYC4J Discovery agent N.A. Investigative [3]
------------------------------------------------------------------------------------
Molecule Interaction Atlas

References

1 Product Pipeline Review of MedImmune, LLC in 2012.
2 Structure-based optimization of potent and selective inhibitors of the tyrosine kinase erythropoietin producing human hepatocellular carcinoma receptor B4 (EphB4). J Med Chem. 2009 Oct 22;52(20):6433-46.
3 Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. J Med Chem. 2013 Apr 11;56(7):2936-47.