Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTG8HIM)

• DTT Name: Dual specificity protein phosphatase 1 (DUSP1) DTT Info
• Gene Name: DUSP1

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Avastin+/-Tarceva	DMA86FL	Non-small-cell lung cancer	2C25.Y	Phase 3	[1]

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-ethoxynaphthalene-1,2-dione	DMUN7KC	Discovery agent	N.A.	Investigative	[1]
ADOCIAQUINONE B	DMPOU86	Discovery agent	N.A.	Investigative	[1]
Okadaic acid	DM47CO1	Discovery agent	N.A.	Investigative	[2]

References

• [1] Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem. 2009 Mar 15;17(6):2276-81.
• [2] Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein. Mol Med. 1995 Jul;1(5):535-41.