Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTGM19J)

DTT Name	Inward rectifier potassium channel Kir3.1 (KCNJ3) DTT Info
UniProt ID	KCNJ3_HUMAN
Gene Name	KCNJ3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ML297	DMY40UG	Discovery agent	N.A.	Investigative	[1]
PIP2	DMOZV7N	Discovery agent	N.A.	Investigative	[2]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays antiepileptic properties in mice. ACS Chem Neurosci. 2013 Sep 18;4(9):1278-86.
2	Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature. 1998 Feb 19;391(6669):803-6.