Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTGPNZQ)

DTT Name Polo-like kinase 4 (PLK4) DTT Info
Gene Name PLK4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
CFI-400945 DM3BN4W Breast cancer 2C60-2C65 Phase 2 [1]
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1 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
XMD8-92 DMZIHKY Discovery agent N.A. Investigative [2]
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Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 Functional characterization of CFI-400945, a Polo-like kinase 4 inhibitor, as a potential anticancer agent. Cancer Cell. 2014 Aug 11;26(2):163-76.
2 Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein. Cancer Cell. 2010 Sep 14;18(3):258-67.