Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTHJT3X)

• DTT Name: STAT3 messenger RNA (STAT3 mRNA) DTT Info
• Gene Name: STAT3

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-STAT3	DMDTNFB	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[1]
C188-9	DMOV2ZD	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]

6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 113176	DM5QEP4	Discovery agent	N.A.	Investigative	[3]
ISIS 113187	DM4E6Y8	Discovery agent	N.A.	Investigative	[3]
ISIS 113209	DMGVN7A	Discovery agent	N.A.	Investigative	[3]
ISIS 113210	DMZWH6E	Discovery agent	N.A.	Investigative	[3]
ISIS 17148	DMPZ9D3	Discovery agent	N.A.	Investigative	[3]
ISIS 17152	DME7VZG	Discovery agent	N.A.	Investigative	[3]

References

• [1] Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] US patent application no. 7,098,192, Antisense oligonucleotide modulation of STAT3 expression.