Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTHMW3T)

• DTT Name: Thymic stromal lymphopoietin (TSLP) DTT Info
• Gene Name: TSLP

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tezepelumab	DM9R5J6	Severe asthma	CA23	Approved	[1]

7 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A378	DMUWRTB	Asthma	CA23	IND submitted	[2]
CSJ117	DMZJUV6	Asthma	CA23	Phase 2	[3]
MEDI9929	DMGD1YP	Asthma	CA23	Phase 2	[4]
AMG 104	DM3XC31	Asthma	CA23	Phase 1	[5]
AZD8630	DMMUF0O	Asthma	CA23	Phase 1	[6]
PF-07275315	DMHRVUY	Atopic dermatitis	EA80	Phase 1	[7]
SAR443765	DMLYI4Z	Asthma	CA23	Phase 1	[8]

References

• [1] Tezepelumab in Adults with Uncontrolled Asthma. N Engl J Med. 2017 Sep 7;377(10):936-946.
• [2] Clinical pipeline report, company report or official report of Klus Pharma
• [3] TSLP Inhibitors for Asthma: Current Status and Future Prospects. Drugs. 2020 Apr;80(5):449-458.
• [4] Human immunoglobulin G2Lambda monoclonal antibody directed against thymic stromal lymphopoietin (MEDI9929). European medicines agency science medicines health (EMEA-001613-PIP01-14). European Union. 2015.
• [5] Clinical pipeline report, company report or official report of Amgen
• [6] Clinical pipeline report, company report or official report of AstraZeneca
• [7] Clinical pipeline report, company report or official report of Pfizer
• [8] Clinical pipeline report, company report or official report of Sanofi