Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTHRAPJ)

• DTT Name: G-protein coupled receptor C 5D (GPRC5D) DTT Info
• Gene Name: GPRC5D

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Talquetamab	DMXRENI	Multiple myeloma	2A83	Approved	[1]

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GPRC5D CAR-T cell therapy	DM8MGSH	Multiple myeloma	2A83	Phase 1	[2]
RG6234	DMYUSOJ	Multiple myeloma	2A83	Phase 1	[3]

References

• [1] FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761342
• [2] GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells. Sci Transl Med. 2019 Mar 27;11(485):eaau7746.
• [3] Clinical pipeline report, company report or official report of Roche