Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTILUKB)

• DTT Name: IRAK4 messenger RNA (IRAK4 mRNA) DTT Info
• Gene Name: IRAK4

Molecule-Related Drug & Molecule List

11 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 156449	DMPB3FH	Discovery agent	N.A.	Investigative	[1]
ISIS 156451	DMPH2W7	Discovery agent	N.A.	Investigative	[1]
ISIS 156452	DMCU6RF	Discovery agent	N.A.	Investigative	[1]
ISIS 156453	DMQ9018	Discovery agent	N.A.	Investigative	[1]
ISIS 156471	DMM9ARP	Discovery agent	N.A.	Investigative	[1]
ISIS 156472	DM3U0Z6	Discovery agent	N.A.	Investigative	[1]
ISIS 156473	DMDFUS8	Discovery agent	N.A.	Investigative	[1]
ISIS 156474	DMCXP9T	Discovery agent	N.A.	Investigative	[1]
ISIS 156475	DMNB4UJ	Discovery agent	N.A.	Investigative	[1]
N-(1H-benzo[d]imidazol-2-yl)-3-cyanobenzamide	DM054NF	Discovery agent	N.A.	Investigative	[2]
N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide	DM0CWPX	Discovery agent	N.A.	Investigative	[2]

References

• [1] US patent application no. 6,692,959, Antisense modulation of IL-1 receptor-associated kinase-4 expression.
• [2] Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.