Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJFOAL)

DTT Name	Wee1-like protein kinase (WEE1) DTT Info
UniProt ID	WEE1_HUMAN
Gene Name	WEE1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MK-1775	DM3WDZ5	Ovarian cancer	2C73	Phase 2	[1], [2]
ZN-c3	DM4MSLY	Uterine serous carcinoma	2C72.1	Phase 2	[3]
------------------------------------------------------------------------------------

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione	DMGCX7E	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth. Oncol Rep. 2013 May;29(5):2011-8.
2	Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor. Mol Cancer. 2009 Jun 8;8:34.
3	Clinical pipeline report, company report or official report of Zentalis Pharmaceuticals.
4	Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.