Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJHKYD)

• DTT Name: Delta-aminolevulinic acid dehydratase (ALAD) DTT Info
• Gene Name: ALAD

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aminolevulinic acid hci	DMS4BLQ	Acne vulgaris	ED80	Approved	[1]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Porphobilinogen	DM5HMTB	N. A.	N. A.	Phase 2	[2]

10 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Sulfhydryl-Ethanol	DMJBO3D	Discovery agent	N.A.	Investigative	[2]
3-(2-Aminoethyl)-4-(Aminomethyl)Heptanedioic Acid	DMQXPM3	Discovery agent	N.A.	Investigative	[2]
4,7-Dioxosebacic Acid	DML5302	Discovery agent	N.A.	Investigative	[2]
4-Oxosebacic Acid	DMADSUY	Discovery agent	N.A.	Investigative	[2]
5-Fluorolevulinic Acid	DMDV48S	Discovery agent	N.A.	Investigative	[2]
5-hydroxyvaleric acid	DMIXQG6	Discovery agent	N.A.	Investigative	[3]
Delta-Amino Valeric Acid	DMV7IAK	Discovery agent	N.A.	Investigative	[2]
Formic Acid	DMNFZC6	Discovery agent	N.A.	Investigative	[2]
Laevulinic Acid	DMTZ17V	Discovery agent	N.A.	Investigative	[2]
S,S-(2-Hydroxyethyl)Thiocysteine	DMLPAD8	Discovery agent	N.A.	Investigative	[2]

References

• [1] Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. Nat Biotechnol. 2003 May;21(5):566-9.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] Structure of yeast 5-aminolaevulinic acid dehydratase complexed with the inhibitor 5-hydroxylaevulinic acid. Acta Crystallogr D Biol Crystallogr. 2005 Sep;61(Pt 9):1222-6.