Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJOKD1)

• DTT Name: Cathepsin F (CTSF) DTT Info
• Gene Name: CTSF

Molecule-Related Drug & Molecule List

2 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID27998201-Compound-12	DM8QZNC	Bone cancer	2B5Z	Patented	[1]
PMID27998201-Compound-5	DMVZ0ND	Chronic obstructive pulmonary disease	CA22	Patented	[1]

6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Benzoyl-Arginine-Alanine-Methyl Ketone	DMC7TNF	Discovery agent	N.A.	Investigative	[2]
BENZOYL-TYROSINE-ALANINE-METHYL KETONE	DMIRD8S	Discovery agent	N.A.	Investigative	[3]
HOMOPHENYLALANINYLMETHANE	DMVBTHA	Discovery agent	N.A.	Investigative	[3]
PMID22686657C(R)-26	DM19D7G	Discovery agent	N.A.	Investigative	[4]
WRR-112	DMP761U	Discovery agent	N.A.	Investigative	[2]
WRR-99	DM8ZA6K	Discovery agent	N.A.	Investigative	[2]

References

• [1] Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [4] Selective nitrile inhibitors to modulate the proteolytic synergism of cathepsins S and F. J Med Chem. 2012 Jun 28;55(12):5982-6.