Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJQT60)

DTT Name	TGF-beta-activated kinase 1 (MAP3K7) DTT Info
UniProt ID	M3K7_HUMAN
Gene Name	MAP3K7

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AZ-TAK1	DMD4LGN	Mantle cell lymphoma	2A85.5	Investigative	[1]
NG-25	DMC48D9	Discovery agent	N.A.	Investigative	[2]
PMID23099093C17d	DMWS7O9	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2082).
2	Discovery of type II inhibitors of TGFbeta-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). J Med Chem. 2015 Jan 8;58(1):183-96.
3	Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKepsilon kinases. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7169-73.