Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTK1N5G)

DTT Name	MAPK/ERK kinase kinase 2 (MAP3K2) DTT Info
UniProt ID	M3K2_HUMAN
Gene Name	MAP3K2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CI-1040	DMF3DZX	Discovery agent	N.A.	Investigative	[1]
LLZ16407	DM783BP	Discovery agent	N.A.	Investigative	[1]
Ro092210	DM2DXHO	Discovery agent	N.A.	Investigative	[1]
U0126	DM31OGF	Discovery agent	N.A.	Investigative	[1]
URMC-099	DMCJXWK	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

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References

1	Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci. 2002 Jan;23(1):40-5.
2	Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48.