Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTKIBKM)

DTT Name	Beta-hexosaminidase subunit beta (HEXB) DTT Info
Gene Name	HEXB

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TSHA-101	DMFTPCT	GM2 gangliosidosis	5C56.00	Phase 1/2	[1]
AXO-AAV-GM2	DMISRRC	Tay-sachs disease	5C56.00	Phase 1	[2]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	ClinicalTrials.gov (NCT04798235) Phase 1/2, Open-Label Clinical Study to Evaluate the Safety and Efficacy of Intrathecal TSHA-101 Gene Therapy for Treatment of Infantile Onset GM2 Gangliosidosis. U.S.National Institutes of Health.
2	ClinicalTrials.gov (NCT04669535) A Two-Stage, Dose-Escalation and Safety & Efficacy Study of Bilateral Intraparenchymal Thalamic and Intracisternal/Intrathecal Administration of AXO-AAV-GM2 in Tay-Sachs or Sandhoff Disease. U.S.National Institutes of Health.