Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTLKF5M)

DTT Name	NAD-dependent deacetylase sirtuin-2 (SIRT2) DTT Info
Gene Name	SIRT2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

9 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AC1LFGWU	DMXI3O0	N. A.	N. A.	Patented	[1]
AC1LOJYQ	DMVX9NK	N. A.	N. A.	Patented	[1]
BDBM50363773	DM7TASJ	N. A.	N. A.	Patented	[2]
BDBM50363780	DM46UPM	N. A.	N. A.	Patented	[2]
BDBM50363782	DMUQI15	N. A.	N. A.	Patented	[2]
US9359293, TA	DMA3OI4	N. A.	N. A.	Patented	[3]
US9359293, TB	DMRQ2G4	N. A.	N. A.	Patented	[3]
US9359293, TM	DM0NIB5	N. A.	N. A.	Patented	[3]
ZINC915379	DMW9P6U	N. A.	N. A.	Patented	[1]
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⏷ Show the Full List of 9 Patented Agent(s)

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AGK2	DM26AMU	Discovery agent	N.A.	Investigative	[4]
INDUS-815C	DMLJ645	Retinopathy	9B71	Investigative	[5]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Small molecule activators of NRF2 pathway. US9737525.
2	Aroyl thiourea derivatives. US9365508.
3	Methods of treatment using modulators of SIRT2. US9359293.
4	Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27;317(5837):516-9.
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2708).