Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTLUQ8E)

• DTT Name: Hormone sensitive lipase (LIPE) DTT Info
• Gene Name: LIPE

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BENZYL BENZOATE	DMDPYI5	Infestations of lice and scabies	1G00.Z	Approved	[1]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID15026062C41	DMJGFLD	Pancreatitis	DC31-DC34	Clinical trial	[2]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-(3-methoxybenzylthio)-2-phenylacetic acid	DM21MAU	Discovery agent	N.A.	Investigative	[3]
BIFENOX	DM4MUXT	Discovery agent	N.A.	Investigative	[3]
ETHIOFENCARB	DMQTEDP	Discovery agent	N.A.	Investigative	[3]
NCI-159878	DMTCBLS	Discovery agent	N.A.	Investigative	[3]
NCI-58425	DM9C7GP	Discovery agent	N.A.	Investigative	[3]
OXYBENZONE	DMMZYX6	Discovery agent	N.A.	Investigative	[3]
PMI-008	DMHX704	Obesity	5B81	Investigative	[4]

References

• [1] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
• [2] Carbazates as potent inhibitors of hormone-sensitive lipase. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1741-4.
• [3] Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94.
• [4] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2593).