Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTMR5UV)

DTT Name	Alkaline phosphatase tissue-nonspecific (ALPL) DTT Info
Gene Name	ALPL

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Asfotase alfa	DMM4FXA	Genetic disease	8E02	Approved	[1]
Levamisole	DM5EN79	Parasitic infection	1D0Y-1G2Z	Approved	[2]
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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DS-1211	DMY3T0L	Pseudoxanthoma elasticum	EC40	Phase 2	[3]
ALXN1850	DMSQPCT	Hypophosphatasia	5C64.3	Phase 1	[4]
ALXN1910	DMDXTAE	Discovery agent	N.A.	Phase 1	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Enzyme-replacement therapy in life-threatening hypophosphatasia. N Engl J Med. 2012 Mar 8;366(10):904-13.
2	Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity. Braz J Med Biol Res. 2008 Jul;41(7):600-9.
3	In Vitro and In Vivo Pharmacological Profiles of DS-1211, a Novel Potent, Selective, and Orally Bioavailable Tissue-Nonspecific Alkaline Phosphatase Inhibitor. J Bone Miner Res. 2022 Oct;37(10):2033-2043.
4	Clinical pipeline report, company report or official report of Alexion