Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTMW94E)

• DTT Name: FK506-binding protein 1A (FKBP1A) DTT Info
• Gene Name: FKBP1A

Molecule-Related Drug & Molecule List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GPI-1485	DM64ZYM	Parkinson disease	8A00.0	Phase 2	[1]
SDZ-281-240	DMPZ67G	Pruritus	EC90	Phase 2	[2]
AP1903	DM2LU8M	Transplant rejection	NE84	Phase 1/2	[3]

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gpi-1046	DMD5WK4	Parkinson disease	8A00.0	Terminated	[4]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-Hydroxy-2-Butanone	DM7BQ65	Discovery agent	N.A.	Investigative	[5]
FKB-001	DM9K834	Discovery agent	N.A.	Investigative	[5]
Heptyl-Beta-D-Glucopyranoside	DMPQBN0	Discovery agent	N.A.	Investigative	[6]
L-709,587	DM9KCYQ	Discovery agent	N.A.	Investigative	[5]
Methyl Methylsulfinylmethyl Sulfide	DMOCXLW	Discovery agent	N.A.	Investigative	[5]
MYRISTIC ACID	DMYX0BL	Discovery agent	N.A.	Investigative	[4]
Rapamycin Immunosuppressant Drug	DM678IB	Discovery agent	N.A.	Investigative	[5]

References

• [1] Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42.
• [2] Clearing of psoriasis by a novel immunosuppressive macrolide. J Invest Dermatol. 1996 Apr;106(4):701-10.
• [3] Using gene transfer to circumvent off-target effects. Gene Ther. 2008 May;15(10):759-64.
• [4] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [5] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [6] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.