Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTMY6BZ)

DTT Name	PDZ binding kinase (PBK) DTT Info
Gene Name	PBK

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
HITOPK-032	DM7MUJ3	Nasopharyngeal carcinoma	2B6B	Investigative	[1]
OTS964	DMXP72F	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival.Oncotarget. 2016 May 3;7(18):26604-16.
2	TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. Sci Transl Med. 2014 Oct 22;6(259):259ra145.