Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTNDSC3)

• DTT Name: B lymphocyte kinase (BLK) DTT Info
• UniProt ID: BLK_HUMAN
• Gene Name: BLK

Molecule-Related Drug & Molecule List

1 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pyrazolo[4,3-c]pyridine derivative 2	DMCDFLQ	N. A.	N. A.	Patented	[1]

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID15546730C2	DMOPUIH	Discovery agent	N.A.	Investigative	[2]
PMID24915291C31	DMN7QB8	Discovery agent	N.A.	Investigative	[3]
PMID24915291C38	DMBXT9J	Discovery agent	N.A.	Investigative	[3]

References

• [1] Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1.Expert Opin Ther Pat. 2017 Feb;27(2):127-143.
• [2] Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6061-6.
• [3] Discovery of a series of 2,5-diaminopyrimidine covalent irreversible inhibitors of Bruton's tyrosine kinase with in vivo antitumor activity. J Med Chem. 2014 Jun 26;57(12):5112-28.