Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQ916P)

DTT Name	Fibroblast growth factor-21 (FGF21) DTT Info
Gene Name	FGF21

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pegozafermin	DM5D7VG	Hypertriglyceridemia	5C80.1	Phase 3	[1]
BMS-986036	DMIZKEC	Type-2 diabetes	5A11	Phase 2	[2]
PF-05231023	DMQYBSH	Type-2 diabetes	5A11	Phase 1	[3]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FGF-21	DMB35UN	Type-2 diabetes	5A11	Discontinued in Phase 1/2	[4]
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Molecule Interaction Atlas

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References

1	Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study. Lancet Gastroenterol Hepatol. 2023 Feb;8(2):120-132.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Mechanistic investigation of the preclinical pharmacokinetics and interspecies scaling of PF-05231023, a fibroblast growth factor 21-antibody protein conjugate. Drug Metab Dispos. 2015 Jun;43(6):803-11.
4	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028644)