Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQ9RYT)

DTT Name	Endothelin-converting enzyme 1 (ECE1) DTT Info
Gene Name	ECE1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SCH-54470	DMEWLZ7	N. A.	N. A.	Terminated	[1]
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9 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
5-(2-hydroxyethyl)nonane-1,9-diol	DMHBD1T	Discovery agent	N.A.	Investigative	[2]
CGS 35066	DMCHT27	Discovery agent	N.A.	Investigative	[3]
LY-292223	DML36ZE	Discovery agent	N.A.	Investigative	[4]
PD159790	DM6RVTO	Discovery agent	N.A.	Investigative	[5]
PMID19899765C22	DMBTV20	Discovery agent	N.A.	Investigative	[1]
PO3 2-Ile-Trp-O-3K	DMQMDSG	Discovery agent	N.A.	Investigative	[6]
PO3 2-Leu-Nal-O-3K	DMY43FU	Discovery agent	N.A.	Investigative	[6]
PO3 2-Leu-Trp-O-3K	DM3O78D	Discovery agent	N.A.	Investigative	[6]
PO3 2-Nle-Trp-O-3K	DMW1XY4	Discovery agent	N.A.	Investigative	[6]
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⏷ Show the Full List of 9 Investigative Drug(s)

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors. J Med Chem. 2010 Jan 14;53(1):208-20.
2	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
3	The therapeutic potential of endothelin-1 receptor antagonists and endothelin-converting enzyme inhibitors on the cardiovascular system. Expert Opin Investig Drugs. 2002 Nov;11(11):1537-52.
4	Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells. J Med Chem. 2005 Jan 27;48(2):483-98.
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1615).
6	Aminophosphonate endothelin converting enzyme inhibitors: potency-enhancing and selectivity-improving modifications of phosphoramidon, Bioorg. Med. Chem. Lett. 4(10):1257-1262 (1994).