Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQBMPI)

DTT Name	Na(+)/Cl(-) betaine/GABA transporter (SLC6A12) DTT Info
Gene Name	SLC6A12

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(R)-EF-1520	DM297MU	Discovery agent	N.A.	Investigative	[1]
(R/S) EF-1500	DMYDG27	Discovery agent	N.A.	Investigative	[1]
(S)-EF-1520	DM0EQTM	Discovery agent	N.A.	Investigative	[1]
LU32-176B	DM2YOVC	Discovery agent	N.A.	Investigative	[2]
NNC052090	DMCGF3U	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 932).
2	First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anti... J Pharmacol Exp Ther. 2005 Feb;312(2):866-74.
3	1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter. Br J Pharmacol. 1997 Mar;120(6):983-5.