General Information of DTT (ID: TTQFRP0)

DTT Name MEK kinase kinase 2 (MAP4K2) DTT Info
UniProt ID
M4K2_HUMAN
Gene Name MAP4K2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Investigative Drug(s)
Clinical Trial Drug(s)
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinazoline derivative 9 DMP3QSA Breast cancer 2C60-2C65 Phase 1 [1]
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1 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
NG-25 DMC48D9 Discovery agent N.A. Investigative [2]
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Molecule Interaction Atlas

References

1 Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
2 Discovery of type II inhibitors of TGFbeta-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). J Med Chem. 2015 Jan 8;58(1):183-96.