General Information of DTT (ID: TTRA5BZ)

DTT Name Steroid 17-alpha-monooxygenase (S17AH) DTT Info
UniProt ID
CP17A_HUMAN
Gene Name CYP17A1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
2 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABIRATERONE DM8V75C Prostate cancer 2C82.0 Approved [1], [2]
Abiraterone acetate DMANBZI Prostate cancer 2C82.0 Approved [3]
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4 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
TAK-700 DM2H8FZ Prostate cancer 2C82.0 Phase 3 [4]
Seviteronel DM9IMEZ Breast cancer 2C60-2C65 Phase 2 [5]
CFG920 DM2BXDU Prostate cancer 2C82.0 Phase 1/2 [6]
DST-2970 DM69ZBU Prostate cancer 2C82.0 Phase 1 [7]
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89 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
1-((9H-Fluoren-2-yl)ethyl)-1H-imidazole DMGRV8U Discovery agent N.A. Investigative [8]
1-((9H-Fluoren-2-yl)methyl)-1H-imidazole DMPBJ9L Discovery agent N.A. Investigative [8]
1-(1-(4'-Ethylbiphenyl-4-yl)propyl)-1H-imidazole DMOQPKT Discovery agent N.A. Investigative [8]
1-(1-(4-thiophen-3-yl-phenyl)propyl)-1Himidazole DMQF2N5 Discovery agent N.A. Investigative [9]
1-(1-(4-thiophen-3-ylphenyl)ethyl)-1H-imidazole DMEIH5N Discovery agent N.A. Investigative [9]
1-(1-(Biphenyl-4-yl)allyl)-1H-imidazole DMLJ7WA Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-2-methyl-propyl)-1H-imidazole DMPEIQT Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-2-phenyl-ethyl)-1H-imidazole DMCTF8X Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-3-methyl-butyl)-1H-imidazole DMWME7I Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-butyl)-1H-imidazole DM4XILF Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-ethyl)-1H-imidazole DMW85CH Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-pentyl)-1H-imidazole DM3AD7E Discovery agent N.A. Investigative [8]
1-(1-Biphenyl-4-yl-propyl)-1H-imidazole DMGVE3F Discovery agent N.A. Investigative [8]
1-(3,4-dichlorobenzyl)-1H-imidazole DMX6PKO Discovery agent N.A. Investigative [10]
1-(3,4-difluorobenzyl)-1H-imidazole DMRXD2P Discovery agent N.A. Investigative [10]
1-(3,5-bis(trifluoromethyl)benzyl)-1H-imidazole DM5WOK8 Discovery agent N.A. Investigative [10]
1-(3,5-dibromobenzyl)-1H-imidazole DMNRCM0 Discovery agent N.A. Investigative [10]
1-(3,5-dichlorobenzyl)-1H-imidazole DMLSWHP Discovery agent N.A. Investigative [10]
1-(3,5-difluorobenzyl)-1H-imidazole DMEAI6V Discovery agent N.A. Investigative [10]
1-(3-(4-chlorophenyl)propyl)-1H-imidazole DMIFARP Discovery agent N.A. Investigative [11]
1-(3-(4-fluorophenyl)propyl)-1H-imidazole DMWKXZ2 Discovery agent N.A. Investigative [11]
1-(3-phenylpropyl)-1H-imidazole DMPAWFJ Discovery agent N.A. Investigative [11]
1-(4-Bromobenzyl)-1H-imidazole DM2C7U0 Discovery agent N.A. Investigative [11]
1-(4-bromophenethyl)-1H-imidazole DME8B15 Discovery agent N.A. Investigative [11]
1-(4-chlorobenzyl)-1H-imidazole DMBR9TQ Discovery agent N.A. Investigative [11]
1-(4-chlorophenethyl)-1H-imidazole DM9MDZG Discovery agent N.A. Investigative [11]
1-(4-fluorobenzyl)-1H-imidazole DMBJCGA Discovery agent N.A. Investigative [11]
1-(4-iodobenzyl)-1H-imidazole DMM17I0 Discovery agent N.A. Investigative [12]
1-(4-methyl-benzyl)-1H-imidazole DM48ISZ Discovery agent N.A. Investigative [10]
1-(4-nitrobenzyl)-1H-imidazole DMKT2MB Discovery agent N.A. Investigative [10]
1-(Bis-biphenyl-4-yl-methyl)-1H-imidazole DMF3D5R Discovery agent N.A. Investigative [8]
1-Ethyl-5-(imidazol-1-yl-phenyl-methyl)-1H-indole DMUOSJG Discovery agent N.A. Investigative [13]
1-Imidazol-1-ylmethyl-4-nitro-xanthen-9-one DMN7KHS Discovery agent N.A. Investigative [14]
1-Imidazol-1-ylmethylxanthen-9-one DMIDX7P Discovery agent N.A. Investigative [15]
2,3,4,5-Tetrafluoro-6-pentafluorophenylazo-phenol DMGQE4B Discovery agent N.A. Investigative [16]
2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol DMRVYKQ Discovery agent N.A. Investigative [16]
2-(1-Imidazol-1-yl-ethyl)-9H-carbazole DM4MIXK Discovery agent N.A. Investigative [8]
3-(1-Chloro-7-methoxy-naphthalen-2-yl)-pyridine DMLH7YI Discovery agent N.A. Investigative [17]
3-(1-ethyl-3,4-dihydronaphthalen-2-yl)-pyridine DMR7M82 Discovery agent N.A. Investigative [18]
3-(1-methyl-3,4-dihydronaphthalen-2-yl)-pyridine DMU5HMC Discovery agent N.A. Investigative [18]
3-(6-Ethoxy-naphthalen-2-yl)-pyridine DMUQ0WI Discovery agent N.A. Investigative [17]
3-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine DMAJHXO Discovery agent N.A. Investigative [18]
3-(6-methoxynaphthalen-2-yl)pyridine DMYRJAB Discovery agent N.A. Investigative [19]
3-fluoro-4'-(1-(pyridin-4-yl)propyl)biphenyl-4-ol DM4PLSU Discovery agent N.A. Investigative [20]
3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol DMJ3WNP Discovery agent N.A. Investigative [21]
3-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine DMHISM2 Discovery agent N.A. Investigative [21]
3-[4-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine DMPS340 Discovery agent N.A. Investigative [22]
4'-(1-(pyridin-4-yl)propyl)biphenyl-3-ol DMEW1CP Discovery agent N.A. Investigative [20]
4'-(2-methyl-1-(pyridin-4-yl)propyl)biphenyl-3-ol DM6DSNI Discovery agent N.A. Investigative [20]
4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine DMZ0H5X Discovery agent N.A. Investigative [21]
4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol DM6Z5EK Discovery agent N.A. Investigative [21]
4'-(Pyridin-4-ylmethyl)biphenyl-3-amine DMR8O1B Discovery agent N.A. Investigative [21]
4'-(Pyridin-4-ylmethyl)biphenyl-4-amine DM8HXYS Discovery agent N.A. Investigative [21]
4'-(Pyridin-4-ylmethyl)biphenyl-4-carboxamide DMYXMT6 Discovery agent N.A. Investigative [21]
4-((1H-imidazol-1-yl)methyl)benzonitrile DMFUBRC Discovery agent N.A. Investigative [10]
4-((1H-imidazol-1-yl)methyl)phenol DMYDGH4 Discovery agent N.A. Investigative [12]
4-((3',4'-Difluorobiphenyl-4-yl)methyl)pyridine DMHN5OL Discovery agent N.A. Investigative [21]
4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine DM52NMU Discovery agent N.A. Investigative [21]
4-(4-(thiophen-2-yl)benzyl)pyridine DMVXJU6 Discovery agent N.A. Investigative [21]
4-(4-(thiophen-3-yl)benzyl)pyridine DM7I21V Discovery agent N.A. Investigative [21]
4-Bromo-1-imidazol-1-ylmethyl-xanthen-9-one DMMVASI Discovery agent N.A. Investigative [14]
4-Indan-(1Z)-ylidenemethyl-pyridine DM25DR7 Discovery agent N.A. Investigative [22]
4-[(3'-Hydroxybiphenyl-4-yl)methyl]pyridine DM04MK7 Discovery agent N.A. Investigative [21]
4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine DMIEMWA Discovery agent N.A. Investigative [21]
4-[1-(4'-Methoxybiphenyl-4-yl)propyl]pyridine DMCEABJ Discovery agent N.A. Investigative [21]
4-[4-(6-methoxynaphthalen-2-yl)benzyl]pyridine DM62351 Discovery agent N.A. Investigative [21]
4-[5-Bromo-indan-(1E)-ylidenemethyl]-pyridine DMI7YAQ Discovery agent N.A. Investigative [22]
4-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine DMQKHXN Discovery agent N.A. Investigative [22]
4-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine DMZL8KN Discovery agent N.A. Investigative [22]
4-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine DM1Z3DG Discovery agent N.A. Investigative [22]
4-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine DMY08FE Discovery agent N.A. Investigative [22]
4-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine DMHDZUO Discovery agent N.A. Investigative [22]
5-[4-(Pyridin-4-ylmethyl)phenyl]-1H-indole DMW8RLN Discovery agent N.A. Investigative [21]
5-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyrimidine DM2RIHT Discovery agent N.A. Investigative [22]
6-(3-(pyridin-4-yl)phenyl)naphthalen-2-ol DMA8TWC Discovery agent N.A. Investigative [23]
6-(pyridin-3-yl)-2-naphthonitrile DMC3SJI Discovery agent N.A. Investigative [19]
6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione DMHAS2B Discovery agent N.A. Investigative [19]
6-Pyridin-3-yl-naphthalen-2-ol DMGWNDB Discovery agent N.A. Investigative [17]
6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol DM40LQ9 Discovery agent N.A. Investigative [21]
7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol DMRPFNU Discovery agent N.A. Investigative [8]
ANG-3407 DMVI93X Prostate cancer 2C82.0 Investigative [24]
ISOCONAZOLE DMMF1HX Discovery agent N.A. Investigative [25]
N-(4'-Isonicotinoylbiphenyl-3-yl)acetamide DM2N3TG Discovery agent N.A. Investigative [21]
N-3-(4-bromophenyl)propyl imidazole DMFRD09 Discovery agent N.A. Investigative [11]
Rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3,4-diol DMTN7IU Discovery agent N.A. Investigative [26]
Rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3,5-diol DMQYRAB Discovery agent N.A. Investigative [26]
Rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3-ol DMH2CX5 Discovery agent N.A. Investigative [26]
Rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-4-ol DMUQ6FW Discovery agent N.A. Investigative [26]
VN/107-1 DMJRI6A Prostate cancer 2C82.0 Investigative [24]
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⏷ Show the Full List of 89 Investigative Drug(s)
Molecule Interaction Atlas

References

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15 Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation. J Med Chem. 2010 Jul 22;53(14):5347-51.
16 Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis. J Med Chem. 1990 Sep;33(9):2452-5.
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18 Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B... J Med Chem. 2006 Apr 6;49(7):2222-31.
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22 Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitor... J Med Chem. 2005 Mar 10;48(5):1563-75.
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