Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTT46BN)

• DTT Name: Bromodomain and PHD finger containing 1 (BRPF1) DTT Info
• Gene Name: BRPF1

Molecule-Related Drug & Molecule List

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NI-57	DM52ITO	Discovery agent	N.A.	Investigative	[1]
OF-1	DMK8LEC	Discovery agent	N.A.	Investigative	[1]
PFI-4	DMPKXNZ	Discovery agent	N.A.	Investigative	[1]
PMID25408830C1	DM5GL23	Discovery agent	N.A.	Investigative	[2]
PMID25408830C2	DM20E13	Discovery agent	N.A.	Investigative	[2]
PMID25408830C3	DM8SBR2	Discovery agent	N.A.	Investigative	[2]
PMID25974391C34	DMGWZA3	Discovery agent	N.A.	Investigative	[3]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2730).
• [2] 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. ACS Med Chem Lett. 2014 Sep 10;5(11):1190-5.
• [3] Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF. J Med Chem. 2016 Feb 25;59(4):1642-7.