Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTT6LOU)

DTT Name	Insulin-like growth factor-I (IGF1) DTT Info
Gene Name	IGF1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Xentuzumab	DM4ZIDH	Breast cancer	2C60-2C65	Phase 2	[1]
BI-836845	DM4T916	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
MEDI-573	DMNL8MO	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Pharmacodynamic and antineoplastic activity of BI 836845, a fully human IGF ligand-neutralizing antibody, and mechanistic rationale for combination with rapamycin.Mol Cancer Ther.2014 Feb;13(2):399-409.
3	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.