General Information of DTT (ID: TTTLB3R)

DTT Name Mycobacterium Membrane protein mmpL3 (MycB mmpL3) DTT Info
Gene Name MycB mmpL3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
SQ-109 DMWK9BX Bacterial infection 1A00-1C4Z Phase 2 [1]
BM-212 DMIRX3Z Asthma CA23 Phase 1 [2]
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Molecule Interaction Atlas

References

1 SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1797-809.
2 MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrob Agents Chemother. 2012 Jan;56(1):324-31.