Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTU3WV6)

• DTT Name: SRSF protein kinase 1 (SRPK1) DTT Info
• Gene Name: SRPK1

Molecule-Related Drug & Molecule List

3 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sphinx	DMJF6S0	N. A.	N. A.	Patented	[1]
SPHINX scaffold, 3	DM8XJTH	N. A.	N. A.	Patented	[1]
ZINC959121	DMR0F4H	N. A.	N. A.	Patented	[1]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SPHINX31	DMYZQKC	Wet age-related macular degeneration	9B78.3Z	Preclinical	[2]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID15925511C13	DMHY95J	Discovery agent	N.A.	Investigative	[3]

References

• [1] Piperazine derivatives for treating disorders. US9695160.
• [2] Kinase inhibitors: the road ahead. Nat Rev Drug Discov. 2018 May;17(5):353-377.
• [3] Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3241-6.