Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTVK4ZO)

DTT Name	G protein coupled receptor 81 (HCAR1) DTT Info
Gene Name	HCAR1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
3,5-dihydroxybenzoic acid	DM04N7I	Discovery agent	N.A.	Investigative	[1]
D-lactic acid	DMBNFQ8	Discovery agent	N.A.	Investigative	[2]
L-lactic acid	DMO1Z5Q	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J Pharmacol Exp Ther. 2012 Jun;341(3):794-801.
2	Role of GPR81 in lactate-mediated reduction of adipose lipolysis. Biochem Biophys Res Commun. 2008 Dec 19;377(3):987-91.
3	Screening beta-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors. J Biomol Screen. 2013 Jun;18(5):599-609.