Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTVW6QL)

DTT Name	CSF1R messenger RNA (CSF1R mRNA) DTT Info
UniProt ID	CSF1R_HUMAN
Gene Name	CSF1R

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GTP-14564	DMW23Y9	Discovery agent	N.A.	Investigative	[1]
GW-2580	DMTW9GM	Discovery agent	N.A.	Investigative	[2]
JNJ-28312141	DMCMH7O	Discovery agent	N.A.	Investigative	[3]
Ki-20227	DM9M3VC	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosin... J Biol Chem. 2003 Aug 29;278(35):32892-8.
2	Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16078-83.
3	Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol. 2011 Oct 30;29(11):1046-51.