Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTW26OG)

DTT Name	Endoplasmic reticulum chaperone BiP (HSPA5) DTT Info
Gene Name	HSPA5

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IT-139	DMBPV9W	Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]
NKP-1339	DM5AWK1	Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]
SAM-6	DMDHQYA	Melanoma	2C30	Phase 1	[2]
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Molecule Interaction Atlas

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References

1	NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer. BMC Pharmacol Toxicol. 2012; 13(Suppl 1): A82.
2	A new tumor-specific variant of GRP78 as target for antibody-based therapy. Lab Invest. 2008 Apr;88(4):375-86.