Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWDKCL)

• DTT Name: Target of rapamycin complex 2 MAPKAP1 (MTORC2) DTT Info
• Gene Name: MAPKAP1

Molecule-Related Drug & Molecule List

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AZD2014	DMOEARH	Solid tumour/cancer	2A00-2F9Z	Phase 2	[1]
ME-344	DM6JN19	Breast cancer	2C60-2C65	Phase 1/2	[1]
Palomid-529	DM428Y3	Alzheimer disease	8A20	Phase 1	[2]
VS-5584	DMMO3G5	Malignant mesothelioma	2C26.0	Phase 1	[3]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the blood-brain barrier without restriction by ABCB1 and ABCG2. Int J Cancer. 2013 Sep 1;133(5):1222-33.
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)