Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWFBT7)

DTT Name	Extracellular matrix receptor III (CD44) DTT Info
Gene Name	CD44

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A-6	DM6ZIES	Macular degeneration	9B78.3	Phase 2	[1]
SPL-108	DMRXCUQ	Ovarian cancer	2C73	Phase 2	[2]
BIWA 4	DM61JH5	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bivatuzumab mertansine	DM0DO4S	Solid tumour/cancer	2A00-2F9Z	Terminated	[3]
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Molecule Interaction Atlas

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References

1	Modulation of CD44 Activity by A6-Peptide.Front Immunol.2015 Mar 30;6:135.
2	Clinical pipeline report, company report or official report of Splash Pharmaceuticals.
3	A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6064-72.