Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWL9TY)

DTT Name	LIM domain kinase-1 (LIMK-1) DTT Info
UniProt ID	LIMK1_HUMAN
Gene Name	LIMK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID19831390C14	DMIECOF	Discovery agent	N.A.	Investigative	[1]
PMID22902653C30	DMXDTPL	Discovery agent	N.A.	Investigative	[2]
PMID22902653C31	DMWVTAE	Discovery agent	N.A.	Investigative	[2]
PMID22902653C35	DMLVKPG	Discovery agent	N.A.	Investigative	[2]
RKI-1447	DMGTAWC	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8.
2	Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8.
3	Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709.