Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWPA54)

• DTT Name: HIF2-alpha messenger RNA (EPAS1 mRNA) DTT Info
• Gene Name: EPAS1

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PT2385	DMCSN69	Recurrent glioblastoma	2A00.00	Phase 2	[1]
ARO-HIF2	DMV5PEK	Renal cell carcinoma	2C90	Phase 1	[2]

5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 222001	DMD7HA3	Discovery agent	N.A.	Investigative	[3]
ISIS 222035	DMQY2EA	Discovery agent	N.A.	Investigative	[3]
ISIS 222039	DMVL1SN	Discovery agent	N.A.	Investigative	[3]
ISIS 222041	DMS03TR	Discovery agent	N.A.	Investigative	[3]
ISIS 222043	DM26M7E	Discovery agent	N.A.	Investigative	[3]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] National Cancer Institute Drug Dictionary (drug name ARO-HIF2).
• [3] US patent application no. 7,217,572, Modulation of HIF1.alpha. and HIF2.alpha. expression.