Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTXDOHN)

DTT Name	Free fatty acid receptor 3 (FFAR3) DTT Info
Gene Name	FFAR3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(S)-4-CMTB	DMI12X9	Discovery agent	N.A.	Investigative	[1]
1-methylcyclopropanecarboxylic acid	DMDIH07	Discovery agent	N.A.	Investigative	[2]
isobutyric acid	DMX4VY9	Discovery agent	N.A.	Investigative	[3]
pentanoic acid	DM56RAX	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol. 2008 Dec;74(6):1599-609.
2	Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. J Biol Chem. 2011 Mar 25;286(12):10628-40.
3	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1045-50.