Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTXMI0C)

DTT Name	Phosphomevalonate kinase (PMVK) DTT Info
Gene Name	PMVK

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(R)-5-diphosphomevalonate	DMOESL1	Discovery agent	N.A.	Investigative	[1]
3-hydroxy-3-methyl-6-phosphohexanoic acid	DM3YO72	Discovery agent	N.A.	Investigative	[2]
cinnamic acid	DM340FH	Discovery agent	N.A.	Investigative	[3]
isoferulic acid	DMN23KT	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Functional evaluation of conserved basic residues in human phosphomevalonate kinase. Biochemistry. 2007 Oct 23;46(42):11780-8.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 641).
3	Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds. Biochem J. 1979 Jul 1;181(1):143-51.