Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTXMZ81)

• DTT Name: Prominin-1 (PROM1) DTT Info
• Gene Name: PROM1

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Anti-CD133-CAR vector-transduced T cells	DMGUM90	Brain cancer	2A00	Phase 1	[1]
ICT-121	DM64LVS	Recurrent glioblastoma	2A00.00	Phase 1	[2]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CAR-T cells targeting CD133	DMYOR5T	Acute myeloid leukaemia	2A60	Preclinical	[3]

References

• [1] ClinicalTrials.gov (NCT02541370) Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
• [2] Immunotargeting of cancer stem cells. Contemp Oncol (Pozn) 2015; 19(1A): A52-A59.
• [3] ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia