Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTY2KP7)

• DTT Name: Leucyl-cysteinyl aminopeptidase (LNPEP) DTT Info
• Gene Name: LNPEP

Molecule-Related Drug & Molecule List

7 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US10023583, Example 13	DMU21PD	N. A.	N. A.	Patented	[1]
US10023583, Example 24	DM5LK6O	N. A.	N. A.	Patented	[1]
US10023583, Example 5	DMZR10T	N. A.	N. A.	Patented	[1]
US10023583, Example 8	DM40KU8	N. A.	N. A.	Patented	[1]
US10059720, Example 80	DMBD95S	N. A.	N. A.	Patented	[2]
US10059720, Example 82	DMJ6GU9	N. A.	N. A.	Patented	[2]
US10059720, Example 84	DMKLVE4	N. A.	N. A.	Patented	[2]

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
inhibitor 19	DMWIHRX	Discovery agent	N.A.	Investigative	[3]
PMID23916253C17	DM35FH8	Discovery agent	N.A.	Investigative	[4]

References

• [1] Bicyclic pyridine compound. US10023583.
• [2] Pyridine derivative. US10059720.
• [3] Potent macrocyclic inhibitors of insulin-regulated aminopeptidase (IRAP) by olefin ring-closing metathesis. J Med Chem. 2011 Jun 9;54(11):3779-92.
• [4] Novel selective inhibitors of aminopeptidases that generate antigenic peptides. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4832-6.