Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYA75N)

DTT Name	MHC class II antigen DR (HLA-DR) DTT Info
Gene Name	HLA-DRA

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Apolizumab	DMKVP7E	Solid tumour/cancer	2A00-2F9Z	Phase 2	[1]
AEA-35p	DMQRKXP	Influenza virus infection	1E30-1E32	Phase 1	[2]
IMMU-114	DMTFUM4	Haematological malignancy	2B33.Y	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: a pilot study.
2	WO patent application no. 2013,1850,32, Nanotherapeutics for drug targeting.
3	The humanized anti-HLA-DR moAb, IMMU-114, depletes APCs and reduces alloreactive T cells: implications for preventing GVHD. Bone Marrow Transplant. 2012 Jul;47(7):967-80.